Key features and details
- Rabbit polyclonal to MAGT1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MAGT1 antibody
See all MAGT1 primary antibodies
DescriptionRabbit polyclonal to MAGT1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Horse, Guinea pig, Cat, Dog, Pig
Synthetic peptide, corresponding to a region within N terminal amino acids 4-53 (RWRFWCVSVT MVVALLIVCD VPSASAQRKK EMVLSEKVSQ LMEWTNKRPV) of Human MAGT1 (UniProt Q9H0U3)
- Human fetal brain lysate
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS, 2% Sucrose
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab90478 in the following tested applications.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
RelevanceMAGT1 is a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in MAGT1 cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.
Cellular localizationEndoplasmic reticulum membrane; Multi-pass membrane protein
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ab90478 has been referenced in 3 publications.
- Wang G et al. microRNA-199a-5p suppresses glioma progression by inhibiting MAGT1. J Cell Biochem N/A:N/A (2019). PubMed: 31038761
- Zheng K et al. Overexpression of MAGT1 is associated with aggressiveness and poor prognosis of colorectal cancer. Oncol Lett 18:3857-3862 (2019). PubMed: 31516596
- Gu Y et al. TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/ß-catenin and MAPK signalling. J Pathol 239:60-71 (2016). PubMed: 27071482