Anti-MAL antibody (ab15418)
Key features and details
- Rabbit polyclonal to MAL
- Suitable for: WB
- Reacts with: Mouse, Xenopus laevis
- Isotype: IgG
Overview
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Product name
Anti-MAL antibody
See all MAL primary antibodies -
Description
Rabbit polyclonal to MAL -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Xenopus laevis -
Immunogen
Synthetic peptide corresponding to Human MAL aa 114-126.
Sequence:CFDGFTY(R/K)HYHENI
(Peptide available asab39812) -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: 99% PBS, 0.1% BSA -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15418 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | (1) |
1/500. Detects a band of approximately 17 kDa (predicted molecular weight: 18 kDa).
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Notes |
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WB
1/500. Detects a band of approximately 17 kDa (predicted molecular weight: 18 kDa). |
Target
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Function
Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function. -
Sequence similarities
Belongs to the MAL family.
Contains 1 MARVEL domain. -
Developmental stage
Expressed in the intermediate and late stages of T-cell differentiation. -
Post-translational
modificationsLipoprotein. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 17153 Mouse
- SwissProt: O09198 Mouse
- Unigene: 39040 Mouse
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Alternative names
- mal antibody
- MAL protein gene antibody
- Mal T-cell differentiation protein antibody
see all
Images
Protocols
Datasheets and documents
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Datasheet download
References (4)
ab15418 has been referenced in 4 publications.
- Wang N et al. Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile. Int J Mol Sci 22:N/A (2021). PubMed: 33672337
- Lv H et al. MicroRNA-150 contributes to ischemic stroke through its effect on cerebral cortical neuron survival and function by inhibiting ERK1/2 axis via Mal. J Cell Physiol 234:1477-1490 (2019). PubMed: 30144062
- Carmosino M et al. MAL/VIP17, a new player in the regulation of NKCC2 in the kidney. Mol Biol Cell 21:3985-97 (2010). ICC/IF, IP ; Rat, Dog . PubMed: 20861303
- Kamsteeg EJ et al. MAL decreases the internalization of the aquaporin-2 water channel. Proc Natl Acad Sci U S A 104:16696-701 (2007). IP ; Rat . PubMed: 17940053