Overview

  • Product name

  • Description

    Rabbit polyclonal to MAN1A2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human MAN1A2 aa 62-101.
    Sequence:

    KHKRFDLGLEDVLIPHVDAGKGAKNPGVFLIHGPDEHRHR


    Database link: O60476

  • Positive control

    • A431 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab220865 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.

Target

  • Relevance

    MAN1A2 plays a role in the maturation of Asn-linked oligosaccharides (N-glycans) in mammalian cells, by progressively excising alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
  • Cellular localization

    Golgi apparatus membrane; Single-pass type II membrane protein
  • Database links

  • Alternative names

    • Alpha 1,2 mannosidase IB antibody
    • MAN1B antibody
    • Mannosidase alpha class 1A member 2 antibody
    • Mannosyl oligosaccharide 1,2 alpha mannosidase IB antibody
    • Processing alpha 1,2 mannosidase IB antibody
    see all

Images

  • Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized A431 cells labeling MAN1A2 with ab220865 at 4 μg/ml (green).

References

ab220865 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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