Key features and details
- Rabbit polyclonal to Mannan Binding Lectin/MBL
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Mannan Binding Lectin/MBL antibody
See all Mannan Binding Lectin/MBL primary antibodies
DescriptionRabbit polyclonal to Mannan Binding Lectin/MBL
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Chimpanzee, Cynomolgus monkey, Gorilla
Recombinant full length protein corresponding to Human Mannan Binding Lectin/MBL aa 21-248. Mature protein.
ETVTCEDAQKTCPAVIACSSPGINGFPGKDGRDGTKGEKGEPGQGLRGLQ GPPGKLGPPGNPGPSGSPGPKGQKGDPGKSPDGDSSLAASERKALQTEMA RIKKWLTFSLGKQVGNKFFLTNGEIMTFEKVKALCVKFQASVATPRNAAE NGAIQNLIKEEAFLGITDEKTEGQFVDLTGNRLTYTNWNEGEPNNAGSDE DCVLLLKNGQWNDVPCSTSHLAVCEFPI
Database link: P11226
- HepG2, Mouse liver and mouse pancreas extracts.
This product was previously labelled as Mannan Binding Lectin
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189856 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 26 kDa.|
|IHC-P||1/50 - 1/200.|
FunctionCalcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Tissue specificityPlasma protein produced mainly in the liver.
Involvement in diseaseNote=There is an association between low levels of MBL2 and a defect of opsonization which results in susceptibility to frequent and chronic infections.
Sequence similaritiesContains 1 C-type lectin domain.
Contains 1 collagen-like domain.
- Information by UniProt
- COLEC 1 antibody
- COLEC1 antibody
- Collectin-1 antibody
ab189856 has been referenced in 1 publication.
- Li YL et al. Screening and identification of differentially expressed serum proteins in patients with vitiligo using two-dimensional gel electrophoresis coupled with mass spectrometry. Mol Med Rep 17:2651-2659 (2018). PubMed: 29207142