Key features and details
- Potent, competitve adenylyl cyclase inhibitor. Fluorescent GTP derivative. eIF5B substrate.
- CAS Number: 136749-24-1
- Purity: > 90%
- Supplied in water (10 mM)
- Form / State: Liquid
- Source: Synthetic
Product nameMant-GTPgammaS (aqueous solution), adenylyl cyclase inhibitor
DescriptionPotent, competitve adenylyl cyclase inhibitor. Fluorescent GTP derivative. eIF5B substrate.
Biological descriptionPotent, competitive adenylyl cyclase inhibitor. Fluorescent GTP-γ-S (ab146662) derivative. eIF5B substrate. Noncompetitively inhibits GTP-γ-S-stimulated adenylyl cyclase in Galpha(s)-expressing Sf9 insect cell membranes.
Storage instructionsStore at -20°C (desiccating conditions).
Solubility overviewSupplied in water (10 mM)
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146758 has been referenced in 1 publication.
- Kanie T et al. The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base. Dev Cell 42:22-36.e12 (2017). PubMed: 28625565