Key features and details
- Rabbit polyclonal to MAP1
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-MAP1 antibody
See all MAP1 primary antibodies
DescriptionRabbit polyclonal to MAP1
Specificityab25954 recognises MAP-1.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
A 15 amino acid synthetic peptide from near the center of MAP-1(Human)
- EL4 cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab25954 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 40 kDa.|
FunctionRequired for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.
Tissue specificityUbiquitously expressed with higher levels in heart and brain.
Sequence similaritiesBelongs to the PNMA family.
DomainThe BH3-like domain is required for association with BAX and for mediating apoptosis. The three BH domains (BH1, BH2, and BH3) of BAX are all required for mediating protein-protein interaction.
- Information by UniProt
- MAP 1 antibody
- MAP-1 antibody
- MAP1 antibody
Lane 1 : Anti-MAP1 antibody (ab25954) at 1 µg/ml
Lane 2 : Anti-MAP1 antibody (ab25954) at 2 µg/ml
Lane 3 : Anti-MAP1 antibody (ab25954) at 4 µg/ml
All lanes : EL4 cell lysate.
Predicted band size: 40 kDa
Observed band size: ~35 kDa why is the actual band size different from the predicted?
ab25954 has been referenced in 2 publications.
- Wills J et al. Tauopathic Changes in the Striatum of A53T a-Synuclein Mutant Mouse Model of Parkinson's Disease. PLoS One 6:e17953 (2011). PubMed: 21445308
- Haggerty T et al. Hyperphosphorylated Tau in an a-synuclein-overexpressing transgenic model of Parkinson's disease. Eur J Neurosci 33:1598-610 (2011). PubMed: 21453448