Product nameAnti-MAP2 antibody [MT-08]
See all MAP2 primary antibodies
DescriptionMouse monoclonal [MT-08] to MAP2
Tested applicationsSuitable for: WB, IP, ELISA, IHC-P, IHC-Fr, ICCmore details
Species reactivityReacts with: Cow, Human
Predicted to work with: Mouse, Pig
Full length native protein (purified) corresponding to Cow MAP2 aa 1375-1395.
- Human Cortex tissue
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab118898 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 199 kDa.|
|IP||Use at an assay dependent concentration.|
|ELISA||Use at an assay dependent concentration.|
|IHC-P||Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|IHC-Fr||Use at an assay dependent concentration.|
|ICC||Use at an assay dependent concentration.|
FunctionThe exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules.
Sequence similaritiesContains 3 Tau/MAP repeats.
modificationsPhosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly (By similarity). Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67.
Cellular localizationCytoplasm, cytoskeleton.
- Information by UniProt
- DKFZp686I2148 antibody
- MAP 2 antibody
- MAP dendrite specific antibody
ab118898 has not yet been referenced specifically in any publications.