Overview

  • Product name
    Anti-MAP3K4 antibody [EP551Y]
    See all MAP3K4 primary antibodies
  • Description
    Rabbit monoclonal [EP551Y] to MAP3K4
  • Host species
    Rabbit
  • Specificity
    This antibody is predicted to detect splice isoform 2 based on sequence analysis.
  • Tested applications
    Suitable for: IHC-P, ICC, Flow Cyt, WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human MAP3K4 aa 150-250.
    Database link: Q9Y6R4

  • General notes

     

    A trial size is available to purchase for this antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab40784 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration.
ICC 1/100 - 1/250.
Flow Cyt 1/20.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

WB 1/1000 - 1/5000. Detects a band of approximately 200 kDa (predicted molecular weight: 182 kDa).
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6.
    • Tissue specificity
      Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues.
    • Sequence similarities
      Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
      Contains 1 protein kinase domain.
    • Cellular localization
      Cytoplasm > perinuclear region. Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles.
    • Information by UniProt
    • Database links
    • Alternative names
      • dJ473J16.1 (mitogen-activated protein kinase kinase kinase 4) antibody
      • FLJ42439 antibody
      • KIAA0213 antibody
      • M3K4_HUMAN antibody
      • MAP three kinase 1 antibody
      • MAP/ERK kinase kinase 4 antibody
      • MAP3K4 antibody
      • MAPK/ERK kinase kinase 4 antibody
      • MAPKKK4 antibody
      • MEK kinase 4 antibody
      • MEKK 4 antibody
      • MEKK4 antibody
      • Mitogen-activated protein kinase kinase kinase 4 antibody
      • MTK1 antibody
      • predicted protein of HQ0412 antibody
      • PRO0412 antibody
      • RP3-473J16.4 antibody
      • SSK2/SSK22 MAP kinase kinase kinase, yeast, homolog of antibody
      see all

    Images

    • Anti-MAP3K4 antibody [EP551Y] (ab40784) at 1/1000 dilution + 293 cell lysate. at 10 µg

      Predicted band size: 182 kDa
      Observed band size: 200 kDa
      why is the actual band size different from the predicted?

    • Immunohistochemical analysis of paraffin-embedded human ovary adenocarcinoma using ab40784.

    References

    ab40784 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab40784.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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