Overview

  • Product name

  • Description

    Rabbit polyclonal to MAPK 13
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human MAPK 13. (Near the C terminal; NP_002745).
    Database link: O15264

  • Positive control

    • Mouse intestinum tenue tissue lysate; Human colon cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab199149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.
WB 1/500 - 1/2000. Predicted molecular weight: 42 kDa.

Target

  • Function

    Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K.
  • Tissue specificity

    Expressed in testes, pancreas, small intestine, lung and kidney. Abundant in macrophages, also present in neutrophils, CD4+ T-cells, and endothelial cells.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
    Contains 1 protein kinase domain.
  • Domain

    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
  • Post-translational
    modifications

    Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
  • Information by UniProt
  • Database links

  • Alternative names

    • MAP kinase 13 antibody
    • MAP kinase p38 delta antibody
    • MAPK 13 antibody
    • MAPK-13 antibody
    • Mapk13 antibody
    • MGC99536 antibody
    • Mitogen activated protein kinase 13 antibody
    • Mitogen-activated protein kinase 13 antibody
    • Mitogen-activated protein kinase p38 delta antibody
    • MK13_HUMAN antibody
    • OTTHUMP00000016282 antibody
    • OTTHUMP00000016283 antibody
    • p38 delta antibody
    • P38delta antibody
    • PRKM13 antibody
    • SAPK 4 antibody
    • SAPK4 antibody
    • Stress activated protein kinase 4 antibody
    • Stress-activated protein kinase 4 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling MAPK 13 with ab199149 at 1/15 dilution.

  • Anti-MAPK 13 antibody (ab199149) at 1/200 dilution + Mouse intestinum tenue tissue lysate at 40 µg

    Predicted band size: 42 kDa


    Exposure time: 1 minute


    Gel: 8%  SDS-PAGE.

References

ab199149 has not yet been referenced specifically in any publications.

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