Overview

  • Product name

    Anti-MAPK11 antibody [EPR6526(2)]
    See all MAPK11 primary antibodies
  • Description

    Rabbit monoclonal [EPR6526(2)] to MAPK11
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide corresponding to residues near the N terminal of Human MAPK11 (UniProt ID: Q15759).

  • Positive control

    • Human cerebellum and fetal brain tissue lysates
  • General notes

    A trial size is available to purchase for this antibody.

    Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR6526(2)
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab137066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 41 kDa.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      Kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. Phosphorylates preferentially transcription factor ATF2.
    • Tissue specificity

      Highest levels in the brain and heart. Also expressed in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
    • Sequence similarities

      Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
      Contains 1 protein kinase domain.
    • Domain

      The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.
    • Post-translational
      modifications

      Dually phosphorylated on Thr-180 and Tyr-182, which activates the enzyme.
    • Information by UniProt
    • Database links

    • Alternative names

      • Human p38Beta MAP kinase mRNA complete cds antibody
      • MAP kinase 11 antibody
      • MAP kinase p38 beta antibody
      • MAPK 11 antibody
      • Mapk11 antibody
      • Mitogen activated protein kinase 11 antibody
      • Mitogen activated protein kinase p38 2 antibody
      • Mitogen activated protein kinase p38 beta antibody
      • Mitogen-activated protein kinase 11 antibody
      • Mitogen-activated protein kinase p38 beta antibody
      • MK11_HUMAN antibody
      • p38 2 antibody
      • p38-2 antibody
      • p38B antibody
      • p38Beta antibody
      • P38BETA2 antibody
      • PRKM11 antibody
      • Protein kinase mitogen activated 11 antibody
      • SAPK2 antibody
      • SAPK2B antibody
      • Stress activated protein kinase 2 antibody
      • Stress activated protein kinase 2b antibody
      • Stress-activated protein kinase 2 antibody
      see all

    Images

    • All lanes : Anti-MAPK11 antibody [EPR6526(2)] (ab137066) at 1/1000 dilution

      Lane 1 : Human cerebellum tissue lysate
      Lane 2 : Human fetal brain tissue lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 41 kDa

    References

    ab137066 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab137066.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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