Overview

  • Product name

    Maprotiline hydrochloride, Noradrenaline reuptake inhibitor
  • Description

    Noradrenaline reuptake inhibitor
  • Biological description

    Noradrenaline reuptake inhibitor. KD values are 11.1, 1000 and 5800 nM for noradrenaline, dopamine and serotonin transporters, respectively. Demonstrates 98% bioavailability following oral administration. Antidepressant activity in vivo.
  • Purity

    > 99%
  • CAS Number

    10347-81-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Brachtendorf L  et al. Cytochrome P450 enzymes contributing to demethylation of maprotiline in man. Pharmacol Toxicol 90:144-9 (2002). Read more (PubMed: 12071336) »
  • Tatsumi M  et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol 340:249-58 (1997). Read more (PubMed: 9537821) »
  • Baumann PA & Maître L Neurobiochemical aspects of maprotiline (Ludiomil) action. J Int Med Res 7:391-400 (1979). Read more (PubMed: 387493) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab120769.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up