Key features and details
- Rabbit polyclonal to MARCH2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Product nameAnti-MARCH2 antibody
See all MARCH2 primary antibodies
DescriptionRabbit polyclonal to MARCH2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Human
- Mouse brain lysate.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab123136 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.|
FunctionE3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
Tissue specificityBroadly expressed.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesContains 1 RING-CH-type zinc finger.
DomainThe RING-CH-type zinc finger domain is required for E3 ligase activity.
Cellular localizationEndoplasmic reticulum membrane. Lysosome membrane. Endosome membrane.
- Information by UniProt
- E3 ubiquitin protein ligase MARCH2 antibody
- E3 ubiquitin-protein ligase MARCH2 antibody
- EC 6.3.2.- antibody
ab123136 has not yet been referenced specifically in any publications.