Anti-MARCKS antibody (ab217695)
Key features and details
- Rabbit polyclonal to MARCKS
- Suitable for: IHC-P
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-MARCKS antibody
See all MARCKS primary antibodies -
Description
Rabbit polyclonal to MARCKS -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Mouse, Human -
Immunogen
Synthetic peptide within Human MARCKS aa 1-100 conjugated to keyhole limpet haemocyanin. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
Database link: P29966 -
Positive control
- IHC-P- Rat brain tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Proclin 300
Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA, 48.98% TBS, 1X
Aqueous buffered solution -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab217695 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/100 - 1/500.
|
Notes |
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IHC-P
1/100 - 1/500. |
Target
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Function
MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. -
Sequence similarities
Belongs to the MARCKS family. -
Post-translational
modificationsPhosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity. -
Cellular localization
Cytoplasm > cytoskeleton. Membrane. - Information by UniProt
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Database links
- Entrez Gene: 4082 Human
- Entrez Gene: 17118 Mouse
- Entrez Gene: 25603 Rat
- Omim: 177061 Human
- SwissProt: P29966 Human
- SwissProt: P26645 Mouse
- SwissProt: P30009 Rat
- Unigene: 519909 Human
see all -
Alternative names
- 80 kDa protein antibody
- 80K L antibody
- 80K L protein antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab217695 has not yet been referenced specifically in any publications.