Overview

  • Product name

  • Description

    Rabbit polyclonal to MARCKS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human MARCKS aa 20-70 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    GEAAVASSPSKANGQENGHVK VNGDASPAAAESGAKEELQA NGSAPAADKE


    Database link: P29966

  • Positive control

    • IHC-P- Rat brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab217695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein.
  • Sequence similarities

    Belongs to the MARCKS family.
  • Post-translational
    modifications

    Phosphorylation by PKC displaces MARCKS from the membrane. It also inhibits the F-actin cross-linking activity.
  • Cellular localization

    Cytoplasm > cytoskeleton. Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 80 kDa protein antibody
    • 80K L antibody
    • 80K L protein antibody
    • 80K-L protein antibody
    • 80KL antibody
    • 81 kDa protein, light chain antibody
    • light chain antibody
    • MACS antibody
    • MARCKS antibody
    • MARCS antibody
    • MARCS_HUMAN antibody
    • MGC52672 antibody
    • myristoylated alanine rich C kinase substrate antibody
    • Myristoylated alanine rich protein kinase C substrate (MARCKS, 80K L) antibody
    • Myristoylated alanine rich protein kinase C substrate antibody
    • Myristoylated alanine-rich C-kinase substrate antibody
    • Phosphomyristin antibody
    • PKCSL antibody
    • PRKCSL antibody
    • protein kinase C substrate 80 kDa protein light chain antibody
    • Protein kinase C substrate antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Rat brain tissue labeling MARCKS with ab217695 at 1/200 followed by conjugation to the secondary antibody and DAB staining.

References

ab217695 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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