• Product name

    Anti-MARVELD1 antibody
  • Description

    Rabbit polyclonal to MARVELD1
  • Host species

  • Specificity

    Specific for MARVELD1. Does not bind to other MARVELD proteins.
  • Tested applications

    Suitable for: ELISA, WB, ICC/IFmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    16 amino acids synthetic peptide from the N terminal region of Human MARVELD1 (EAW49903).

  • Positive control

    • Mouse heart tissue lysate This antibody gave a positive result when used in the following methanol fixed cell lines: PC3


  • Form

  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab91640 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 19 kDa.
ICC/IF Use a concentration of 5 µg/ml.


  • Function

    Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration.
  • Tissue specificity

    Widely expressed in normal tissues. Down-regulated in multiple primary tumors.
  • Sequence similarities

    Contains 1 MARVEL domain.
  • Cellular localization

    Cell membrane. Cytoplasm > cytoskeleton. Nucleus. Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization.
  • Information by UniProt
  • Database links

  • Alternative names

    • GB14 antibody
    • MALD1_HUMAN antibody
    • MARVD1 antibody
    • MARVEL (membrane-associating) domain containing 1 antibody
    • MARVEL domain containing protein 1 antibody
    • MARVEL domain-containing protein 1 antibody
    • MARVELD1 antibody
    • MRVLDC1 antibody
    • Putative MARVEL domain containing protein 1 antibody
    see all


  • ICC/IF image of ab91640 stained PC3 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab91640 at 5µg/ml overnight at +4°C. The secondary antibody (pseudo-colored green) was Alexa Fluor® 488 goat anti- rabbit (ab150081) IgG (H+L) preadsorbed, used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (pseudo-colored red) at a 1/200 dilution for 1h at room temperature. DAPI was used to stain the cell nuclei (pseudo-colored blue) at a concentration of 1.43µM for 1hour at room temperature.

  • Lane 1 : Anti-MARVELD1 antibody (ab91640) at 1 µg/ml
    Lane 2 : Anti-MARVELD1 antibody (ab91640) at 2 µg/ml

    All lanes : Mouse heart lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 19 kDa


This product has been referenced in:

  • Liu W  et al. MARVELD1 depletion leads to dysfunction of motor and cognition via regulating glia-dependent neuronal migration during brain development. Cell Death Dis 9:999 (2018). Read more (PubMed: 30250269) »
  • Wieczfinska J  et al. The whole-genome expression analysis of peripheral blood mononuclear cells from aspirin sensitive asthmatics versus aspirin tolerant patients and healthy donors after in vitro aspirin challenge. Respir Res 16:147 (2015). WB . Read more (PubMed: 26646719) »
See all 3 Publications for this product

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