Overview

  • Product name

    Anti-MASH1/Achaete-scute homolog 1 antibody [EPR19592]
    See all MASH1/Achaete-scute homolog 1 primary antibodies
  • Description

    Rabbit monoclonal [EPR19592] to MASH1/Achaete-scute homolog 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human MASH1/Achaete-scute homolog 1 aa 50-150. The exact sequence is proprietary.
    Database link: P50553

  • Positive control

    • IHC-P: Human medullary thyroid carcinoma and lung small cell carcinoma tissues.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab213151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Target

  • Function

    May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Activates transcription by binding to the E box (5'-CANNTG-3').
  • Sequence similarities

    Contains 1 basic helix-loop-helix (bHLH) domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Achaete scute complex homolog 1 antibody
    • Achaete scute complex homolog like 1 antibody
    • Achaete scute complex homologue 1 antibody
    • Achaete scute complex homologue like 1 antibody
    • Achaete scute complex like 1 antibody
    • Achaete scute family bHLH transcription factor 1 antibody
    • Achaete scute protein antibody
    • Achaete-scute homolog 1 antibody
    • Ascl 1 antibody
    • ascl1 antibody
    • ASCL1_HUMAN antibody
    • Ash 1 antibody
    • ASH-1 antibody
    • Ash1 antibody
    • bHLHa46 antibody
    • Class A basic helix-loop-helix protein 46 antibody
    • Hash 1 antibody
    • HASH1 antibody
    • Mammalian achaete scute homolog 1 antibody
    • Mammalian achaete scute homologue 1 antibody
    • Mash 1 antibody
    • Mash1 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded human lung small cell carcinoma tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution. Nuclear staining on human lung small cell carcinoma is observed. Counter stained with Hematoxylin.

    Secondary antibody only control: Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution.

  • Immunohistochemical analysis of paraffin-embedded human medullary thyroid carcinoma tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution. Nuclear staining on human medullary thyroid carcinoma is observed. Counter stained with Hematoxylin.

    Secondary antibody only control: Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution.

  • Immunohistochemical analysis of paraffin-embedded human lung tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution. Negative staining on human lung. Counter stained with Hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded human thyroid tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution. Negative staining on human thyroid. Counter stained with Hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded human lung squamous cell carcinoma tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution.

    Negative staining on human lung squamous cell carcinoma.

    Counter stained with Hematoxylin.

  • Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue labeling MASH1/Achaete-scute homolog 1 with ab213151 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) at 1/500 dilution. Negative staining on human lung adenocarcinoma.

    Counter stained with Hematoxylin.

References

ab213151 has not yet been referenced specifically in any publications.

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