Anti-Mast Cell Tryptase antibody [AA1] (ab2378)

Mouse monoclonal Mast Cell Tryptase antibody [AA1]. Validated in WB, ELISA, IHC, ICC, ICC/IF and tested in Mouse, Rat, Human. Cited in 38 publication(s). Independently reviewed in 32 review(s).

Publishing research using ab2378? Please let us know so that we can cite the reference in this datasheet.

ab2378 has been referenced in 50 publications.

  • Kan C  et al. BMP-dependent, injury-induced stem cell niche as a mechanism of heterotopic ossification. Stem Cell Res Ther 10:14 (2019). PubMed: 30635039
  • Xiong Y  et al. Tumor infiltrating mast cells determine oncogenic HIF-2a-conferred immune evasion in clear cell renal cell carcinoma. Cancer Immunol Immunother 68:731-741 (2019). PubMed: 30758643
  • Grisanti LA  et al. Prior ß-blocker treatment decreases leukocyte responsiveness to injury. JCI Insight 5:N/A (2019). PubMed: 30920389
  • Liu ZQ  et al. Mast cell infiltration associated with loss of interstitial cells of Cajal and neuronal degeneration in achalasia. Neurogastroenterol Motil 31:e13565 (2019). PubMed: 30868687
  • Coronado M  et al. Soybean Meal-Induced Intestinal Inflammation in Zebrafish Is T Cell-Dependent and Has a Th17 Cytokine Profile. Front Immunol 10:610 (2019). PubMed: 31001250
  • Becker J  et al. Impact of Sensitization and Inflammation on the Interaction of Mast Cells With the Intestinal Epithelium in Rats. Front Physiol 10:329 (2019). PubMed: 30971956
  • Xu W  et al. Electroacupuncture Relieves Visceral Hypersensitivity by Inactivating Protease-Activated Receptor 2 in a Rat Model of Postinfectious Irritable Bowel Syndrome. Evid Based Complement Alternat Med 2018:7048584 (2018). PubMed: 30420896
  • Zhu TH  et al. Estrogen is an important mediator of mast cell activation in ovarian endometriomas. Reproduction 155:73-83 (2018). PubMed: 29074615
  • Zhong C  et al. Developing a diagnostic understanding of GERD phenotypes through the analysis of levels of mucosal injury, immune activation, and psychological comorbidity. Dis Esophagus 31:N/A (2018). PubMed: 29757356
  • Chen LZ  et al. Neuropeptide Initiated Mast Cell Activation by Transcutaneous Electrical Acupoint Stimulation of Acupoint LI4 in Rats. Sci Rep 8:13921 (2018). PubMed: 30224712
  • Trias E  et al. Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS. JCI Insight 3:N/A (2018). PubMed: 30282815
  • Liu DR  et al. Increased intestinal mucosal leptin levels in patients with diarrhea-predominant irritable bowel syndrome. World J Gastroenterol 24:46-57 (2018). IHC-P ; Human . PubMed: 29358881
  • Nakamura T  et al. Ovarian mast cells migrate toward ovary-fimbria connection in neonatal MRL/MpJ mice. PLoS One 13:e0196364 (2018). PubMed: 29684078
  • Kodani M  et al. Association between gastrointestinal motility and macrophage/mast cell distribution in mice during the healing stage after DSS-induced colitis. Mol Med Rep 17:8167-8172 (2018). PubMed: 29693127
  • Yang HW  et al. An investigation of the distribution and location of mast cells affected by the stiffness of substrates as a mechanical niche. Int J Biol Sci 14:1142-1152 (2018). PubMed: 29989093
  • Bahri R  et al. Mast cell activation test in the diagnosis of allergic disease and anaphylaxis. J Allergy Clin Immunol 142:485-496.e16 (2018). PubMed: 29518421
  • Gorth DJ  et al. Transgenic mice overexpressing human TNF-a experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death Dis 10:7 (2018). PubMed: 30584238
  • Wiet MG  et al. Mast Cell-Intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in Discogenic Back Pain. Sci Rep 7:12492 (2017). PubMed: 28970490
  • Niu R  et al. Inhibition of airway inflammation in a cockroach allergen model of asthma by agonists of miRNA-33b. Sci Rep 7:7409 (2017). PubMed: 28785038
  • Zhang L  et al. Stress induces more serious barrier dysfunction in follicle-associated epithelium than villus epithelium involving mast cells and protease-activated receptor-2. Sci Rep 7:4950 (2017). ICC/IF . PubMed: 28694438
  • Chen BR  et al. Fructo-oligosaccharide intensifies visceral hypersensitivity and intestinal inflammation in a stress-induced irritable bowel syndrome mouse model. World J Gastroenterol 23:8321-8333 (2017). IHC ; Mouse . PubMed: 29307992
  • McLeod DS  et al. Mast Cell-Derived Tryptase in Geographic Atrophy. Invest Ophthalmol Vis Sci 58:5887-5896 (2017). PubMed: 29164232
  • Kim DW  et al. IL-25 Could Be Involved in the Development of Allergic Rhinitis Sensitized to House Dust Mite. Mediators Inflamm 2017:3908049 (2017). IHC, RT-PCR . PubMed: 28912627
  • Anastasaki C  et al. KIR2DL5 mutation and loss underlies sporadic dermal neurofibroma pathogenesis and growth. Oncotarget 8:47574-47585 (2017). PubMed: 28548933
  • Lohman RJ  et al. Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a. Nat Commun 8:351 (2017). PubMed: 28839129
  • Spang C  et al. Marked expression of TNF receptors in human peritendinous tissues including in nerve fascicles with axonal damage - Studies on tendinopathy and tennis elbow. J Musculoskelet Neuronal Interact 17:226-236 (2017). PubMed: 28860425
  • Farrugia BL  et al. Mast Cells Produce a Unique Chondroitin Sulfate Epitope. J Histochem Cytochem 64:85-98 (2016). IHC . PubMed: 26586669
  • Lee JY  et al. Repeated Water Avoidance Stress Alters Mucosal Mast Cell Counts, Interleukin-1ß Levels with Sex Differences in the Distal Colon of Wistar Rats. J Neurogastroenterol Motil 22:694-704 (2016). PubMed: 27466288
  • Tamarozzi F  et al. Wolbachia endosymbionts induce neutrophil extracellular trap formation in human onchocerciasis. Sci Rep 6:35559 (2016). IHC-P ; Human . PubMed: 27752109
  • Tellechea A  et al. Mast Cells Regulate Wound Healing in Diabetes. Diabetes 65:2006-19 (2016). PubMed: 27207516
  • Hosseini A  et al. Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects. Part Fibre Toxicol 13:2 (2016). PubMed: 26758251
  • Nizamutdinova IT  et al. Mast cells and histamine are triggering the NF-?B-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation. Aging (Albany NY) 8:3065-3090 (2016). Flow Cyt ; Rat . PubMed: 27875806
  • Mariuzzi L  et al. Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues. Lab Invest 96:959-971 (2016). PubMed: 27348627
  • Chen WC  et al. Decellularized zebrafish cardiac extracellular matrix induces mammalian heart regeneration. Sci Adv 2:e1600844 (2016). IHC . PubMed: 28138518
  • Nishijima H  et al. Denervation of nasal mucosa induced by posterior nasal neurectomy suppresses nasal secretion, not hypersensitivity, in an allergic rhinitis rat model. Lab Invest 96:981-93 (2016). PubMed: 27322954
  • Morishita K  et al. Postinfarction Cardiac Remodeling Proceeds Normally in Granulocyte Colony-Stimulating Factor Knockout Mice. Am J Pathol 185:1899-911 (2015). PubMed: 25976246
  • Maywald RL  et al. IL-33 activates tumor stroma to promote intestinal polyposis. Proc Natl Acad Sci U S A 112:E2487-96 (2015). PubMed: 25918379
  • De Martin S  et al. Expression and distribution of the adrenomedullin system in newborn human thymus. PLoS One 9:e97592 (2014). IHC-P ; Human . PubMed: 24831942
  • Edmunds MC  et al. Paradoxical effects of heme arginate on survival of myocutaneous flaps. Am J Physiol Regul Integr Comp Physiol 306:R10-22 (2014). PubMed: 24089372
  • Kim DK  et al. MBP-positive and CD11c-positive cells are associated with different phenotypes of Korean patients with non-asthmatic chronic rhinosinusitis. PLoS One 9:e111352 (2014). IHC ; Human . PubMed: 25361058
  • Manetti M  et al. Evidence for progressive reduction and loss of telocytes in the dermal cellular network of systemic sclerosis. J Cell Mol Med 17:482-96 (2013). IHC-P ; Human . PubMed: 23444845
  • Meyer J  et al. Mast cell dependent vascular changes associated with an acute response to cold immersion in primary contact urticaria. PLoS One 8:e56773 (2013). IHC-P ; Human . PubMed: 23451084
  • Buniello A  et al. Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One 8:e56274 (2013). IHC-P ; Mouse . PubMed: 23457544
  • Lohman RJ  et al. Antagonism of protease-activated receptor 2 protects against experimental colitis. J Pharmacol Exp Ther 340:256-65 (2012). ICC/IF ; Rat . PubMed: 22028393
  • Campuzano O  et al. Arrhythmogenic right ventricular cardiomyopathy: severe structural alterations are associated with inflammation. J Clin Pathol 65:1077-83 (2012). WB ; Human . PubMed: 22944624
  • Palaniyandi S  et al. CD23-Dependent Transcytosis of IgE and Immune Complex across the Polarized Human Respiratory Epithelial Cells. J Immunol 186:3484-96 (2011). IF ; Human . PubMed: 21307287
  • Palchevskiy V  et al. Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis. Fibrogenesis Tissue Repair 4:10 (2011). PubMed: 21463523
  • Hickey MM  et al. The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice. J Clin Invest 120:827-39 (2010). IHC-P ; Mouse . PubMed: 20197624
  • Zoog SJ  et al. Antagonists of CD117 (cKit) signaling inhibit mast cell accumulation in healing skin wounds. Cytometry A 75:189-98 (2009). IHC-P ; Human, African green monkey . PubMed: 18937342
  • Arena S  et al. Altered 'active' antireflux mechanism in primary vesico-ureteric reflux: a morphological and manometric study. BJU Int 100:407-12 (2007). PubMed: 17532859

For licensing inquiries, please contact

Sign up