Overview

  • Product name

  • Description

    Rabbit polyclonal to MATK
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Mouse MATK aa 476-505 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P41242

  • Positive control

    • Mouse spleen tissue lysate; Mouse brain tissue

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab172875 is purified through a protein A column, followed by immunogen affinity purification.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab172875 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 56 kDa.

Target

  • Function

    Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation.
  • Tissue specificity

    Expressed in various myeloid cell lines, detected in brain and lung.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
    Contains 1 SH3 domain.
  • Post-translational
    modifications

    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • CHK antibody
    • Csk homologous kinase antibody
    • Csk type protein tyrosine kinase antibody
    • CTK antibody
    • DKFZp434N1212 antibody
    • EC 2.7.10.2 antibody
    • Hematopoietic consensus tyrosine lacking kinase antibody
    • Hematopoietic consensus tyrosine-lacking kinase antibody
    • HHYLTK antibody
    • Hydroxyaryl protein kinase antibody
    • HYL antibody
    • HYL tyrosine kinase antibody
    • HYLTK antibody
    • Leukocyte carboxyl terminal src kinase related antibody
    • Lsk antibody
    • matK antibody
    • MATK_HUMAN antibody
    • Megakaryocyte associated tyrosine kinase antibody
    • Megakaryocyte associated tyrosine protein kinase antibody
    • Megakaryocyte-associated tyrosine-protein kinase antibody
    • MGC1708 antibody
    • MGC2101 antibody
    • Protein kinase HYL antibody
    • Tyrosine kinase MATK antibody
    • Tyrosine protein kinase CTK antibody
    • Tyrosine-protein kinase CTK antibody
    • Tyrosylprotein kinase antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded Mouse brain tissue tissue labeling MATK using ab172875 at 1/10 dilution followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • Anti-MATK antibody (ab172875) at 1/100 dilution + Mouse spleen tissue lysate at 35 µg

    Predicted band size: 56 kDa

References

ab172875 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab172875.
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