Overview

  • Product name
  • Description
    Rabbit polyclonal to MATN3
  • Host species
    Rabbit
  • Tested applications
    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human MATN3 (internal sequence). 13 amino acid peptide from near the center of Human MATN3.
    Database link: AAI39908

  • Positive control
    • WB: Rat thymus tissue lysate. ICC/IF: 3T3 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab106388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 53 kDa.
ICC Use a concentration of 2.5 µg/ml.

Target

  • Function
    Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
  • Tissue specificity
    Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.
  • Involvement in disease
    Multiple epiphyseal dysplasia 5
    Spondyloepimetaphyseal dysplasia MATN3-related
    Osteoarthritis 2
  • Sequence similarities
    Contains 4 EGF-like domains.
    Contains 1 VWFA domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AV009181 antibody
    • DIPOA antibody
    • EDM5 antibody
    • HOA antibody
    • MATN3 antibody
    • MATN3_HUMAN antibody
    • Matrilin 3 antibody
    • Matrilin-3 antibody
    • OADIP antibody
    • OS2 antibody
    see all

Images

  • Immmunocytochemistry/Immunofluorescence of MATN3 in 3T3 cells with ab106388 at 20 µg/mL.

  • Lane 1 : Anti-MATN3 antibody (ab106388) at 1 µg/ml
    Lane 2 : Anti-MATN3 antibody (ab106388) at 2 µg/ml

    All lanes : Rat thymus tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 53 kDa

  • Immunocytochemistry of MATN3 in 3T3 cells tissue with ab106388 at 2.5 µg/ml

References

This product has been referenced in:
  • Wu PL  et al. Martrilin-3 (MATN3) Overexpression in Gastric Adenocarcinoma and its Prognostic Significance. Med Sci Monit 24:348-355 (2018). Read more (PubMed: 29343680) »
  • Yang H  et al. Downregulation of microRNA-448 inhibits IL-1ß-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3. Cell Mol Biol Lett 23:7 (2018). Read more (PubMed: 29483929) »
See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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