Overview

  • Product name

    Anti-MATN3/Matrilin-3 antibody
    See all MATN3/Matrilin-3 primary antibodies
  • Description

    Rabbit polyclonal to MATN3/Matrilin-3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WB, ICCmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human MATN3/Matrilin-3 (internal sequence). 13 amino acid peptide from near the center of Human MATN3/Matrilin-3.
    Database link: AAI39908

  • Positive control

    • WB: Rat thymus tissue lysate. ICC/IF: 3T3 cells.
  • General notes

     This product was previously labelled as MATN3

     

Properties

Applications

Our Abpromise guarantee covers the use of ab106388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 53 kDa.
ICC Use a concentration of 2.5 µg/ml.

Target

  • Function

    Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.
  • Tissue specificity

    Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders.
  • Involvement in disease

    Multiple epiphyseal dysplasia 5
    Spondyloepimetaphyseal dysplasia MATN3-related
    Osteoarthritis 2
  • Sequence similarities

    Contains 4 EGF-like domains.
    Contains 1 VWFA domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AV009181 antibody
    • DIPOA antibody
    • EDM5 antibody
    • HOA antibody
    • MATN3 antibody
    • MATN3_HUMAN antibody
    • Matrilin 3 antibody
    • Matrilin-3 antibody
    • OADIP antibody
    • OS2 antibody
    see all

Images

  • Immmunocytochemistry/Immunofluorescence of MATN3/Matrilin-3 in 3T3 cells with ab106388 at 20 µg/mL.

  • Lane 1 : Anti-MATN3/Matrilin-3 antibody (ab106388) at 1 µg/ml
    Lane 2 : Anti-MATN3/Matrilin-3 antibody (ab106388) at 2 µg/ml

    All lanes : Rat thymus tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 53 kDa

  • Immunocytochemistry of MATN3/Matrilin-3 in 3T3 cells tissue with ab106388 at 2.5 µg/ml

References

This product has been referenced in:

  • Wu PL  et al. Martrilin-3 (MATN3) Overexpression in Gastric Adenocarcinoma and its Prognostic Significance. Med Sci Monit 24:348-355 (2018). Read more (PubMed: 29343680) »
  • Yang H  et al. Downregulation of microRNA-448 inhibits IL-1ß-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3. Cell Mol Biol Lett 23:7 (2018). Read more (PubMed: 29483929) »
See all 2 Publications for this product

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