Anti-MATN3/Matrilin-3 antibody (ab238893)
Key features and details
- Rabbit polyclonal to MATN3/Matrilin-3
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-MATN3/Matrilin-3 antibody
See all MATN3/Matrilin-3 primary antibodies -
Description
Rabbit polyclonal to MATN3/Matrilin-3 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, ICC/IFmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human MATN3/Matrilin-3 aa 250 to the C-terminus.
Database link: O15232-1 -
Positive control
- IHC-P: Human kidney and adrenal gland tissue. ICC/IF: HepG2 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab238893 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
1/20 - 1/200.
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ICC/IF |
1/50 - 1/200.
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Notes |
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IHC-P
1/20 - 1/200. |
ICC/IF
1/50 - 1/200. |
Target
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Function
Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks. -
Tissue specificity
Expressed only in cartilaginous tissues, such as vertebrae, ribs and shoulders. -
Involvement in disease
Multiple epiphyseal dysplasia 5
Spondyloepimetaphyseal dysplasia MATN3-related
Osteoarthritis 2 -
Sequence similarities
Contains 4 EGF-like domains.
Contains 1 VWFA domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 4148 Human
- Omim: 602109 Human
- SwissProt: O15232 Human
- Unigene: 656199 Human
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Alternative names
- AV009181 antibody
- DIPOA antibody
- EDM5 antibody
see all
Images
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HepG2 (Human liver hepatocellular carcinoma cell line) cells stained for MATN3/Matrilin-3 (Green) using ab238893 at a dilution of 1/100 in ICC/IF. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).
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Paraffin-embedded human kidney tissue stained for MATN3/Matrilin-3 with ab238893 at a 1/100 dilution in immunohistochemical analysis.
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Paraffin-embedded human adrenal gland tissue stained for MATN3/Matrilin-3 with ab238893 at a 1/100 dilution in immunohistochemical analysis.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab238893 has been referenced in 1 publication.
- Cai WY et al. Identification of a Tumor Microenvironment-relevant Gene set-based Prognostic Signature and Related Therapy Targets in Gastric Cancer. Theranostics 10:8633-8647 (2020). PubMed: 32754268