Overview

  • Product name

  • Description

    Rabbit polyclonal to MC3-R
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cyt, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human MC3-R aa 86-112 (internal sequence) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P41968

  • Positive control

    • IHC-P: Human small intestine and brain (cortex) tissues. WB: K562 cell lysate. Flow: K562 cells.
  • General notes

    Previously labelled as MC3 Receptor. 

Properties

Applications

Our Abpromise guarantee covers the use of ab230451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 40 kDa.
Flow Cyt 1/10 - 1/50.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.
  • Tissue specificity

    Brain, placental, and gut tissues.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BMIQ9 antibody
    • MC3 antibody
    • MC3 R antibody
    • MC3 Receptor antibody
    • MC3-R antibody
    • Mc3r antibody
    • MC3R_HUMAN antibody
    • Melanocortin 3 receptor antibody
    • Melanocortin receptor 3 antibody
    • OB20 antibody
    • Obesity quantitative trait locus antibody
    • OQTL antibody
    see all

Images

  • Anti-MC3-R antibody (ab230451) at 1/1000 dilution + K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate at 35 µg

    Predicted band size: 40 kDa

  • Formalin-fixed, paraffin-embedded human small intestine tissue stained for MC3 Receptor / MC3-R using ab230451 at 1/100 dilution in immunohistochemical analysis.

  • Formalin-fixed, paraffin-embedded human brain (cortex) tissue stained for MC3 Receptor / MC3-R using ab230451 at 1/100 dilution in immunohistochemical analysis.

  • Flow cytometric analysis of K562 (human chronic myelogenous leukemia cell line from bone marrow) cells labeling MC3 Receptor / MC3-R with ab230451 at 1/10 dilution (right histogram) compared to a negetive control (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References

ab230451 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230451.
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