Key features and details
- Rabbit polyclonal to MCC
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MCC antibody
See all MCC primary antibodies
DescriptionRabbit polyclonal to MCC
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow
Recombinant fragment, corresponding to a region within amino acids 1-316 of Human MCC (P23508).
- IMR32 and U-87 MG whole cell lysates; Human Colon carcinoma tissue.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: PBS, 1% BSA, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab125920 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 93 kDa.|
|IHC-P||1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionCandidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.
Tissue specificityExpressed in a variety of tissues.
Sequence similaritiesBelongs to the MCC family.
Cellular localizationCell membrane. Nucleus. Cytoplasm.
- Information by UniProt
- Colorectal mutant cancer protein antibody
- CRCM_HUMAN antibody
- DKFZp762O1615 antibody
ab125920 has not yet been referenced specifically in any publications.