Overview

  • Product name

    Anti-MCC antibody - C-terminal
    See all MCC primary antibodies
  • Description

    Rabbit polyclonal to MCC - C-terminal
  • Host species

    Rabbit
  • Specificity

    No cross reactivity with other proteins.
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human MCC aa 573-590 (C terminal).
    Sequence:

    IQQLKNDRAAVKLTMLEL


    Database link: P23508

  • Positive control

    • Rat brain, 293T, NIH, A549 and HepG2 cell lysates.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
    Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191149 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 93 kDa.

Target

  • Function

    Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.
  • Tissue specificity

    Expressed in a variety of tissues.
  • Sequence similarities

    Belongs to the MCC family.
  • Cellular localization

    Cell membrane. Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Colorectal mutant cancer protein antibody
    • CRCM_HUMAN antibody
    • DKFZp762O1615 antibody
    • FLJ38893 antibody
    • FLJ46755 antibody
    • MCC 1 antibody
    • MCC antibody
    • MCC1 antibody
    • Mutated in colorectal cancers antibody
    • Protein MCC antibody
    see all

Images

  • All lanes : Anti-MCC antibody - C-terminal (ab191149) at 0.5 µg/ml

    Lane 1 : Rat brain lysate
    Lane 2 : 293T cell lysate
    Lane 3 : NIH lysate
    Lane 4 : A549 lysate
    Lane 5 : HepG2 lysate

    Predicted band size: 93 kDa

References

ab191149 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191149.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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