Key features and details
- Rabbit polyclonal to MCCC1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MCCC1 antibody
DescriptionRabbit polyclonal to MCCC1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant fragment corresponding to Human MCCC1 aa 522-696. Genbank: BC004187
MTDTFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHD GSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIYLF SKEGSIEIDIPVPKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAG DSLMVMIAMKMEHTIKSPKDGTVKK
Database link: Q96RQ3
- 293T cell lysate and mouse heart lysate. Human fetal liver tissue.
FormLyophilized:Add 200 µL of sterile distilled water.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab197282 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/1000. Predicted molecular weight: 80 kDa.|
|IHC-P||1/100 - 1/500.|
RelevanceMCCC1 is the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Defects in MCCC1 are the cause of methylcrotonoyl-CoA carboxylase deficiency type 1 (MCC1 deficiency). MCC1 deficiency is an autosomal recessive disorder of leucine catabolism.
Cellular localizationMitochondrion matrix.
- 3-methylcrotonyl-CoA carboxylase 1 antibody
- 3-methylcrotonyl-CoA carboxylase biotin-containing subunit antibody
- 3-methylcrotonyl-CoA carboxylase, alpha antibody
ab197282 has been referenced in 1 publication.
- Sacoman JL et al. Mitochondrial O-GlcNAc Transferase (mOGT) Regulates Mitochondrial Structure, Function, and Survival in HeLa Cells. J Biol Chem 292:4499-4518 (2017). PubMed: 28100784