Key features and details
- Rabbit polyclonal to MCHR-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MCHR-1 antibody
See all MCHR-1 primary antibodies
DescriptionRabbit polyclonal to MCHR-1
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human MCHR-1 (C terminal) conjugated to keyhole limpet haemocyanin.
Database link: NP_005288.3
- Human brain (substantia nigra) tissue.
Previously labelled as MCHR.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -80°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab115474 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 - 18 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
RelevanceMCHR-1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR-1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR-1 does not seem to bind somatostatin.
Cellular localizationCell Membrane; multi-pass membrane protein
- G protein coupled receptor 24 antibody
- GPCR MCH1 antibody
- GPCR SLC/MCH1 antibody
ab115474 has not yet been referenced specifically in any publications.