Overview

  • Product name

  • Description

    Rabbit polyclonal to MCHR-1
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Chimpanzee, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human MCHR-1 (N terminal).
    Database link: NP_005288.3

  • Positive control

    • Human Adrenal tissue.
  • General notes

    Previously labelled as MCHR.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab140881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 15 - 30 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance

    MCHR-1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR-1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR-1 does not seem to bind somatostatin.
  • Cellular localization

    Cell Membrane; multi-pass membrane protein
  • Database links

  • Alternative names

    • G protein coupled receptor 24 antibody
    • GPCR MCH1 antibody
    • GPCR SLC/MCH1 antibody
    • GPR24 antibody
    • MCH 1R antibody
    • MCH receptor 1 antibody
    • MCH-1R antibody
    • MCH-R1 antibody
    • MCH1R antibody
    • MCHR antibody
    • MCHR-1 antibody
    • Melanin concentrating hormone receptor 1 antibody
    • SLC-1 antibody
    • SLC1 antibody
    • Somatostatin receptor like protein antibody
    see all

Images

  • Immunohistochemistry analysis of Formalin fixed and Paraffin Embedded Human adrenal tissue labelling MCHR-1 with ab140881 at 15 µg/ml.

References

ab140881 has not yet been referenced specifically in any publications.

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