Anti-MCHR-1 antibody (ab140881)
Key features and details
- Rabbit polyclonal to MCHR-1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-MCHR-1 antibody
See all MCHR-1 primary antibodies -
Description
Rabbit polyclonal to MCHR-1 -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Chimpanzee, Monkey -
Immunogen
Synthetic peptide corresponding to Human MCHR-1 (N terminal).
Database link: NP_005288.3 -
Positive control
- Human Adrenal tissue.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
IHC-P |
Use a concentration of 15 - 30 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
|
Notes |
---|
IHC-P
Use a concentration of 15 - 30 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
-
Relevance
MCHR-1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR-1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, MCHR-1 does not seem to bind somatostatin. -
Cellular localization
Cell Membrane; multi-pass membrane protein -
Database links
- Entrez Gene: 470220 Chimpanzee
- Entrez Gene: 2847 Human
- Entrez Gene: 207911 Mouse
- Omim: 601751 Human
- SwissProt: Q5IJ49 Chimpanzee
- SwissProt: Q99705 Human
- SwissProt: Q8JZL2 Mouse
-
Alternative names
- G protein coupled receptor 24 antibody
- GPCR MCH1 antibody
- GPCR SLC/MCH1 antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab140881 has not yet been referenced specifically in any publications.