Key features and details
- Mouse polyclonal to MCJ
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-MCJ antibody
See all MCJ primary antibodies
DescriptionMouse polyclonal to MCJ
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
- Lysate of 293T cells transfected with MCJ.
Protein previously labeled as DNAJC15.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.4
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab167199 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 16 kDa.|
FunctionNegative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP (By similarity). Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9.
Tissue specificityExpressed at highest levels in heart, followed by liver and kidney.
Involvement in diseaseAbsent or down-regulated in many advanced cases of ovarian adenocarcinoma, due to hypermethylation and allelic loss. Loss of expression correlates with increased resistance to antineoplastic drugs, such as cisplatin.
Sequence similaritiesContains 1 J domain.
Cellular localizationMitochondrion inner membrane.
- Information by UniProt
- Cell growth inhibiting gene 22 protein antibody
- Cell growth-inhibiting gene 22 protein antibody
- DJC15_HUMAN antibody
ab167199 has not yet been referenced specifically in any publications.