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ab32087 has been referenced in 68 publications.

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  • Mao S  et al. Sirtuin-7 knockdown inhibits the growth of endometrial cancer cells by inducing apoptosis via the NF-?B signaling pathway. Oncol Lett 17:937-943 (2019). PubMed: 30655851
  • Li H  et al. Downregulation of MCL-1 and upregulation of PUMA using mTOR inhibitors enhance antitumor efficacy of BH3 mimetics in triple-negative breast cancer. Cell Death Dis 9:137 (2018). PubMed: 29374168
  • Pan BL  et al. Effects of MicroRNA-206 on Osteosarcoma Cell Proliferation, Apoptosis, Migration and Invasion by Targeting ANXA2 Through the AKT Signaling Pathway. Cell Physiol Biochem 45:1410-1422 (2018). PubMed: 29462818
  • Tsafou K  et al. Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers. Oncotarget 9:31018-31031 (2018). PubMed: 30123424
  • Chen W  et al. MicroRNA-146a-5p enhances ginsenoside Rh2-induced anti-proliferation and the apoptosis of the human liver cancer cell line HepG2. Oncol Lett 16:5367-5374 (2018). PubMed: 30197683
  • Xu R  et al. BC094916 suppressed SP 2/0 xenograft tumor by down-regulating Creb1 and Bcl2 transcription. Cancer Cell Int 18:138 (2018). PubMed: 30220882
  • Wang S  et al. miR-124 regulates STAT3-mediated cell proliferation, migration and apoptosis in bladder cancer. Oncol Lett 16:5875-5881 (2018). PubMed: 30344738
  • Lin J  et al. FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells. Cancer Sci 109:1001-1011 (2018). WB ; Human . PubMed: 29427543
  • Huang Y  et al. LINC00152 down-regulated miR-193a-3p to enhance MCL1 expression and promote gastric cancer cells proliferation. Biosci Rep 38:N/A (2018). PubMed: 29339419
  • Han B  et al. Annonaceous acetogenin mimic AA005 suppresses human colon cancer cell growth in vivo through downregulation of Mcl-1. Acta Pharmacol Sin N/A:N/A (2018). PubMed: 29921883
  • Ma L  et al. Long non-coding RNA XIST promotes cell growth and invasion through regulating miR-497/MACC1 axis in gastric cancer. Oncotarget 8:4125-4135 (2017). WB ; Human . PubMed: 27911852
  • Nijhuis A  et al. MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8. Cell Tissue Res 368:325-335 (2017). PubMed: 28190086
  • Singh PK  et al. Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis. Genes Dev 31:1754-1769 (2017). PubMed: 28982759
  • Pang C  et al. miR-206 inhibits the growth of hepatocellular carcinoma cells via targeting CDK9. Cancer Med 6:2398-2409 (2017). WB . PubMed: 28940993
  • Peperzak V  et al. Functional disparities among BCL-2 members in tonsillar and leukemic B-cell subsets assessed by BH3-mimetic profiling. Cell Death Differ 24:111-119 (2017). PubMed: 27689871
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  • Zhang X  et al. Upregulation of microRNA-125b by G-CSF promotes metastasis in colorectal cancer. Oncotarget 8:50642-50654 (2017). WB ; Human . PubMed: 28881590
  • Zhang ZF  et al. MicroRNA-182 downregulates Wnt/ß-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9. Oncotarget 8:101345-101361 (2017). PubMed: 29254169
  • Kozaki T  et al. Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response. Proc Natl Acad Sci U S A 114:2681-2686 (2017). PubMed: 28213497
  • Wu Q  et al. Endothelial growth medium suppresses apoptosis of mesenchymal stem cells in vitro via decrease of miR-29a. Mol Med Rep 16:2675-2681 (2017). PubMed: 28713918
  • Meryet-Figuière M  et al. Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route. Oncol Rep 38:1949-1958 (2017). PubMed: 28791387
  • Ishii N  et al. Reduced FBXW7 expression in pancreatic cancer correlates with poor prognosis and chemotherapeutic resistance via accumulation of MCL1. Oncotarget 8:112636-112646 (2017). PubMed: 29348852
  • Lin J  et al. Mcl-1 inhibitor suppresses tumor growth of esophageal squamous cell carcinoma in a mouse model. Oncotarget 8:114457-114462 (2017). PubMed: 29383093
  • Ohmer M  et al. Anti-apoptotic Bcl-XL but not Mcl-1 contributes to protection against virus-induced apoptosis. Cell Death Dis 7:e2340 (2016). WB . PubMed: 27537523
  • Wu J  et al. Gp130-mediated STAT3 activation by S-propargyl-cysteine, an endogenous hydrogen sulfide initiator, prevents doxorubicin-induced cardiotoxicity. Cell Death Dis 7:e2339 (2016). WB . PubMed: 27537522
  • Jiang ZX  et al. Roscovitine ameliorates endotoxin-induced uveitis through neutrophil apoptosis. Mol Med Rep 14:1083-90 (2016). WB ; Mouse . PubMed: 27279017
  • Li Q  et al. The effects of buthionine sulfoximine on the proliferation and apoptosis of biliary tract cancer cells induced by cisplatin and gemcitabine. Oncol Lett 11:474-480 (2016). WB ; Human . PubMed: 26870236
  • Lopez J  et al. Mito-priming as a method to engineer Bcl-2 addiction. Nat Commun 7:10538 (2016). WB . PubMed: 26833356
  • Hellvard A  et al. Inhibition of CDK9 as a therapeutic strategy for inflammatory arthritis. Sci Rep 6:31441 (2016). WB, IHC-P ; Mouse, Human . PubMed: 27511630
  • Gao ZY  et al. Metformin induces apoptosis via a mitochondria-mediated pathway in human breast cancer cells in vitro. Exp Ther Med 11:1700-1706 (2016). Human . PubMed: 27168791
  • Wang W  et al. FXR agonists enhance the sensitivity of biliary tract cancer cells to cisplatin via SHP dependent inhibition of Bcl-xL expression. Oncotarget 7:34617-29 (2016). WB ; Human . PubMed: 27127878
  • Štarha P  et al. Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes. PLoS One 11:e0165062 (2016). WB ; Mouse . PubMed: 27906967
  • Zhu ZJ  et al. MicroRNA-181a promotes proliferation and inhibits apoptosis by suppressing CFIm25 in osteosarcoma. Mol Med Rep 14:4271-4278 (2016). PubMed: 27633853
  • Zhang H  et al. Genomic analysis and selective small molecule inhibition identifies BCL-X(L) as a critical survival factor in a subset of colorectal cancer. Mol Cancer 14:126 (2015). WB . PubMed: 26134786
  • Bailey ML  et al. Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint. Genetics 201:885-95 (2015). WB ; Human . PubMed: 26354767
  • Martínez A  et al. Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches. PLoS One 10:e0123352 (2015). WB ; Human . PubMed: 25923732
  • Yang L  et al. Wnt modulates MCL1 to control cell survival in triple negative breast cancer. BMC Cancer 14:124 (2014). IHC-P ; Human . PubMed: 24564888
  • Kanatsu-Shinohara M  et al. Skp1-Cullin-F-box (SCF)-type ubiquitin ligase FBXW7 negatively regulates spermatogonial stem cell self-renewal. Proc Natl Acad Sci U S A 111:8826-31 (2014). WB ; Mouse . PubMed: 24879440
  • Fresquet V  et al. Acquired mutations in BCL2 family proteins conferring resistance to the BH3 mimetic ABT-199 in lymphoma. Blood 123:4111-9 (2014). WB ; Human . PubMed: 24786774
  • Huang H  et al. Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation. Cell Death Dis 5:e1482 (2014). PubMed: 25341036
  • Peng YF  et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy 9:2056-68 (2013). WB ; Human . PubMed: 24157892
  • Shim G  et al. Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes. Mol Ther 21:816-24 (2013). WB . PubMed: 23380818
  • Yallapu MM  et al. Novel curcumin-loaded magnetic nanoparticles for pancreatic cancer treatment. Mol Cancer Ther 12:1471-80 (2013). PubMed: 23704793
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  • Buron N  et al. Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization. PLoS One 5:e9924 (2010). WB ; Human . PubMed: 20360986
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  • Bieghs L  et al. The effects of forodesine in murine and human multiple myeloma cells. Adv Hematol 2010:131895 (2010). WB ; Mouse . PubMed: 20981156
  • Staversky RJ  et al. Epithelial Ablation of Bcl-XL Increases Sensitivity to Oxygen without Disrupting Lung Development. Am J Respir Cell Mol Biol : (2009). PubMed: 19880821
  • Mavrakis KJ  et al. Tumorigenic activity and therapeutic inhibition of Rheb GTPase. Genes Dev 22:2178-88 (2008). WB ; Mouse . PubMed: 18708578
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