• Product name
  • Description
    Rabbit polyclonal to MCP1
  • Host species
  • Tested applications
    Suitable for: WB, Neutralising, Sandwich ELISA, IHC-FoFrmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Highly pure (>98%) recombinant rMCAF/MCP-1 (rat Macrophage/Monocyte chemotactic protein-1)



Our Abpromise guarantee covers the use of ab9779 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa. sed in conjunction with compatible secondary reagents the detection limit for recombinant Rat MCP1 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
Neutralising Use a concentration of 4 - 6 µg/ml. Yields one-half maximal inhibition [ND50] of the biological activity of Rat MCP1 (100 ng/ml).
Sandwich ELISA Use a concentration of 0.5 - 2 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat MCP1.
IHC-FoFr Use at an assay dependent concentration.


  • Function
    Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.
  • Sequence similarities
    Belongs to the intercrine beta (chemokine CC) family.
  • Post-translational
    Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant.
  • Cellular localization
  • Information by UniProt
  • Database links
  • Alternative names
    • C-C motif chemokine 2 antibody
    • CCL2 antibody
    • CCL2_HUMAN antibody
    • Chemokine (C C motif) ligand 2 antibody
    • GDCF 2 antibody
    • GDCF-2 antibody
    • GDCF2 antibody
    • HC11 antibody
    • HSMCR30 antibody
    • JE antibody
    • MCAF antibody
    • MCP 1 antibody
    • MCP-1 antibody
    • MCP1 antibody
    • MGC9434 antibody
    • Monocyte chemoattractant protein 1 antibody
    • Monocyte chemotactic and activating factor antibody
    • Monocyte chemotactic protein 1 antibody
    • Monocyte secretory protein JE antibody
    • SCYA2 antibody
    • Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je) antibody
    • Small inducible cytokine A2 antibody
    • Small inducible cytokine subfamily A (Cys Cys), member 2 antibody
    • Small-inducible cytokine A2 antibody
    • SMC CF antibody
    • SMC-CF antibody
    • SMCCF antibody
    see all


  • Immunohistochemical analysis of PFA perfusion fixed frozen rat brain, staining MCP1 with ab9779 at 1 µg/ml. A peroxidase conjugated secondary antibody was added and staining was detected using a fluorescein Tyramide Signal Amplification (TSA™) reagent.


This product has been referenced in:

See 1 Publication for this product

Customer reviews and Q&As

Thank you for contacting us.

I have been in touch with our lab regarding your question about ab9779 anti-MCP1 antibody.

This product has been raised against and tested with the MCP1 protein, ab9780 (https://www.abcam.com/mcp1-pr...

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Thank you for your inquiry. Both of these antibodies are polyclonals raised against full length recombinant proteins. Thus for blocking purposes, a full length recombinant protein would be recommended. I would like to recommend ab9780 for use with...

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Thank you for your enquiry. With regards to Rabbit Anti-Rat MCP-1, we haven't tested this in vivo, but you can dilute in saline if needed. In our neutralization assay we used the anti rat MCP-1 to block the migration (chemotaxis) of human monocyte...

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