Overview

  • Product name

    Anti-MCP2 antibody (Biotin)
    See all MCP2 primary antibodies
  • Description

    Rabbit polyclonal to MCP2 (Biotin)
  • Host species

    Rabbit
  • Conjugation

    Biotin
  • Tested applications

    Suitable for: Sandwich ELISA, WBmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Recombinant full length protein (Mouse)

Properties

Applications

Our Abpromise guarantee covers the use of ab39627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA
WB
  • Application notes
    ELISA(direct): Use at a concentration of 0.15 - 0.3 µg/ml.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 11 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
    • Tissue specificity

      Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Post-translational
      modifications

      N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Alternative names

      • Ccl8 antibody
      • CCL8_HUMAN antibody
      • HC14 antibody
      • MCP-2 antibody
      • MCP-2(6-76) antibody
      • Monocyte chemoattractant protein 2 antibody
      • Monocyte chemotactic protein 2 antibody
      • SCYA10 antibody
      • SCYA8 antibody
      • Small-inducible cytokine A8 antibody
      see all

    References

    ab39627 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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