Overview

  • Product name

    Anti-MCSF Receptor antibody
    See all MCSF Receptor primary antibodies
  • Description

    Rabbit polyclonal to MCSF Receptor
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human MCSF Receptor aa 200-245 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    PGPPALTLVPA ELVRIRGEAA QIVCSASSVD VNFDVFLQHN NTKLA


    Database link: P07333

  • Positive control

    • Human laryngeal cancer and mouse kidney tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab215441 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/500.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
  • Tissue specificity

    Expressed in bone marrow and in differentiated blood mononuclear cells.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C FMS antibody
    • CD 115 antibody
    • CD115 antibody
    • CD115 antigen antibody
    • CFMS antibody
    • Colony stimulating factor 1 receptor antibody
    • Colony stimulating factor I receptor antibody
    • CSF 1 R antibody
    • CSF 1R antibody
    • CSF-1 receptor antibody
    • CSF-1-R antibody
    • CSF1 R antibody
    • CSF1R antibody
    • CSF1R_HUMAN antibody
    • CSFR antibody
    • EC 2.7.10.1 antibody
    • FIM 2 antibody
    • FIM2 antibody
    • FMS antibody
    • FMS proto oncogene antibody
    • FMS protooncogene antibody
    • HDLS antibody
    • M-CSF Receptor antibody
    • M-CSF-R antibody
    • Macrophage colony stimulating factor 1 receptor antibody
    • Macrophage colony stimulating factor I receptor antibody
    • Macrophage colony-stimulating factor 1 receptor antibody
    • McDonough feline sarcoma viral (v fms) oncogene homolog antibody
    • MCSFR antibody
    • Oncogen FMS antibody
    • Proto-oncogene c-Fms antibody
    • V-FMS McDonough feline sarcoma viral oncogen homolog, formerly antibody
    see all

Images

  • Immunohistochemical analysis of paraformaldehyde-fixed, paraffin-embedded mouse kidney tissue labeling MCSF Receptor with ab215441 at 1/500 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human laryngeal cancer tissue labeling MCSF Receptor with ab215441 at 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • ab215441 staining MCSF in U251 cells by ICC/IF (Immunocytochemistry/ Immunofluorescence). Cells were fixed with Paraformaldehyde, permeablized with 0.3% Triton-100  for 20 minutes and blocked with normal goat serum at 37oC for 30 minutes. Samples were incubated with ab215441 at 1:200 dilution overnight at 4oC. Conjugated Goat anti- rabbit IgG FITC was used as a secondary antibody and incubated for 90 minutes. DAPI used as counterstain. 

     

References

ab215441 has not yet been referenced specifically in any publications.

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