Overview

  • Product name

    Anti-MCSF Receptor antibody
    See all MCSF Receptor primary antibodies
  • Description

    Goat polyclonal to MCSF Receptor
  • Host species

    Goat
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cat
  • Immunogen

    Synthetic peptide corresponding to Human MCSF Receptor aa 700-710 (internal sequence) (Cysteine residue). (NP_005202.2).
    Sequence:

    C-KNIHLEKKYVR


    Database link: P07333

  • Positive control

    • WB: HEK-293 lysate overexpressing human MCSF Receptor with C-terminal MYC tag.

Properties

Applications

Our Abpromise guarantee covers the use of ab223642 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 108 kDa.

Target

  • Function

    Protein tyrosine-kinase transmembrane receptor for CSF1 and IL34.
  • Tissue specificity

    Expressed in bone marrow and in differentiated blood mononuclear cells.
  • Sequence similarities

    Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • C FMS antibody
    • CD 115 antibody
    • CD115 antibody
    • CD115 antigen antibody
    • CFMS antibody
    • Colony stimulating factor 1 receptor antibody
    • Colony stimulating factor I receptor antibody
    • CSF 1 R antibody
    • CSF 1R antibody
    • CSF-1 receptor antibody
    • CSF-1-R antibody
    • CSF1 R antibody
    • CSF1R antibody
    • CSF1R_HUMAN antibody
    • CSFR antibody
    • EC 2.7.10.1 antibody
    • FIM 2 antibody
    • FIM2 antibody
    • FMS antibody
    • FMS proto oncogene antibody
    • FMS protooncogene antibody
    • HDLS antibody
    • M-CSF Receptor antibody
    • M-CSF-R antibody
    • Macrophage colony stimulating factor 1 receptor antibody
    • Macrophage colony stimulating factor I receptor antibody
    • Macrophage colony-stimulating factor 1 receptor antibody
    • McDonough feline sarcoma viral (v fms) oncogene homolog antibody
    • MCSFR antibody
    • Oncogen FMS antibody
    • Proto-oncogene c-Fms antibody
    • V-FMS McDonough feline sarcoma viral oncogen homolog, formerly antibody
    see all

Images

  • Lane 1 : Anti-MCSF Receptor antibody (ab223642) at 0.5 µg/ml
    Lane 2 : Anti-MCSF Receptor antibody (ab223642) at 1 mg/ml
    Lane 3 : Anti-MYC tag at 1/1000 dilution

    Lanes 1 & 3 : HEK-293 (human epithelial cell line from embryonic kidney) lysate overexpressing human MCSF Receptor with C-terminal MYC tag (in RIPA buffer)
    Lane 2 : Mock transfected HEK-293 (human epithelial cell line from embryonic kidney) lysate (in RIPA buffer)

    Lysates/proteins at 10 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 108 kDa
    Observed band size: 200 kDa
    why is the actual band size different from the predicted?



    Primary incubations were for 1 hour.

References

ab223642 has not yet been referenced specifically in any publications.

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