Overview

  • Product name

  • Description

    Rabbit polyclonal to MCT2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from human MCT2 protein

  • Positive control

    • Testis, spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocytes.

Properties

Applications

Our Abpromise guarantee covers the use of ab81262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/400. Predicted molecular weight: 52 kDa.

Target

  • Function

    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.
  • Tissue specificity

    High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
  • Sequence similarities

    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MCT 2 antibody
    • MCT antibody
    • Monocarboxylate transporter 2 antibody
    • MonocarboxylateTransporter 2 antibody
    • MOT2 antibody
    • MOT2_HUMAN antibody
    • SLC16A7 antibody
    • Solute carrier family 16 (monocarboxylate transporter), member 7 antibody
    • Solute carrier family 16 member 7 antibody
    • Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody
    • Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody
    see all

References

This product has been referenced in:

  • Silva ECA  et al. The clinicopathological significance of monocarboxylate transporters in testicular germ cell tumors. Oncotarget 9:20386-20398 (2018). Read more (PubMed: 29755659) »
See 1 Publication for this product

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