Overview

  • Product name

  • Description

    Rabbit polyclonal to MCT2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Recombinant fragment
    Predicted to work with: Mouse
  • Immunogen

    A synthetic peptide corresponding to N terminal residues of Mouse MCT2

Properties

Applications

Our Abpromise guarantee covers the use of ab93049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 52 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA 1/2000 - 1/5000.

Target

  • Function

    Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. MCT2 is a high affinity pyruvate transporter.
  • Tissue specificity

    High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
  • Sequence similarities

    Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • MCT 2 antibody
    • MCT antibody
    • Monocarboxylate transporter 2 antibody
    • MonocarboxylateTransporter 2 antibody
    • MOT2 antibody
    • MOT2_HUMAN antibody
    • SLC16A7 antibody
    • Solute carrier family 16 (monocarboxylate transporter), member 7 antibody
    • Solute carrier family 16 member 7 antibody
    • Solute carrier Family 16 Monocarboxylic Acid Transporters Member 7 antibody
    • Solute carrier family 16, member 7 (monocarboxylic acid transporter 2) antibody
    see all

References

ab93049 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Application
Western blot
Sample
Human Cell lysate - whole cell (Vascular Smooth Muscle Cell)
Gel Running Conditions
Reduced Denaturing
Loading amount
30 µg
Specification
Vascular Smooth Muscle Cell
Blocking step
Milk as blocking agent for 3 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C

Abcam user community

Verified customer

Submitted Jul 20 2016

Application
Western blot
Loading amount
35 µg
Gel Running Conditions
Reduced Denaturing (10% 37.5:1)
Sample
Pig Tissue lysate - whole (Skeletal muscle)
Specification
Skeletal muscle
Blocking step
Thermo Starting Block 37542 as blocking agent for 30 hour(s) and 0 minute(s) · Concentration: 100% · Temperature: 22°C

Abcam user community

Verified customer

Submitted Apr 18 2014

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