Overview

  • Product name

    MDBN, p97 inhibitor
  • Description

    Potent, irreversible p97 inhibitor
  • Biological description

    Potent, irreversible p97 inhibitor. Also inhibits Tyrosine kinase. Inhibits growth and induces apoptosis in tumor cells.
  • Purity

    > 98%
  • CAS Number

    1485-00-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Messerschmitt PJ  et al. Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-ß-nitrostyrene. Sarcoma 2012:479712 (2012). Read more (PubMed: 22701331) »
  • Wang WY  et al. Synthesis and pharmacological evaluation of novel beta-nitrostyrene derivatives as tyrosine kinase inhibitors with potent antiplatelet activity. Biochem Pharmacol 74:601-11 (2007). Read more (PubMed: 17601492) »
  • Wang WY  et al. Prevention of platelet glycoprotein IIb/IIIa activation by 3,4-methylenedioxy-beta-nitrostyrene, a novel tyrosine kinase inhibitor. Mol Pharmacol 70:1380-9 (2006). Read more (PubMed: 16837624) »

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