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ab11169 has been referenced in 34 publications.

  • Chan YW  et al. Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations. Nat Cell Biol 20:92-103 (2018). PubMed: 29255170
  • Gustafsson NMS  et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun 9:3872 (2018). PubMed: 30250201
  • Svobodová Kovaríková A  et al. H3K9me3 and H4K20me3 represent the epigenetic landscape for 53BP1 binding to DNA lesions. Aging (Albany NY) 10:2585-2605 (2018). PubMed: 30312172
  • Guo T  et al. Harnessing accurate non-homologous end joining for efficient precise deletion in CRISPR/Cas9-mediated genome editing. Genome Biol 19:170 (2018). PubMed: 30340517
  • Huang D  et al. Isoorientin triggers apoptosis of hepatoblastoma by inducing DNA double-strand breaks and suppressing homologous recombination repair. Biomed Pharmacother 101:719-728 (2018). WB ; Human . PubMed: 29524880
  • Avgousti DC  et al. Adenovirus core protein VII down-regulates the DNA damage response on the host genome. J Virol N/A:N/A (2017). PubMed: 28794020
  • Zhao MJ  et al. Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy. Oncotarget 7:8956-67 (2016). IF . PubMed: 26788910
  • Lima M  et al. Dual inhibition of ATR and ATM potentiates the activity of trabectedin and lurbinectedin by perturbing the DNA damage response and homologous recombination repair. Oncotarget 7:25885-901 (2016). PubMed: 27029031
  • Cristini A  et al. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res 44:1161-78 (2016). ICC/IF ; Human . PubMed: 26578593
  • Renaud E  et al. Impaired TIP60-mediated H4K16 acetylation accounts for the aberrant chromatin accumulation of 53BP1 and RAP80 in Fanconi anemia pathway-deficient cells. Nucleic Acids Res 44:648-56 (2016). ICC/IF ; Human . PubMed: 26446986
  • Hedström E  et al. Downregulation of the cancer susceptibility protein WRAP53ß in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcome. Cell Death Dis 6:e1892 (2015). PubMed: 26426684
  • Rassoolzadeh H  et al. The proximity ligation assay reveals that at DNA double-strand breaks WRAP53ß associates with ?H2AX and controls interactions between RNF8 and MDC1. Nucleus 6:417-24 (2015). PubMed: 26734725
  • Wang C  et al. MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer. Nucleic Acids Res 43:4893-908 (2015). IHC . PubMed: 25934801
  • Liang H  et al. Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing. Nat Commun 5:4048 (2014). WB ; Human . PubMed: 24893992
  • Wang R  et al. Global discovery of high-NaCl-induced changes of protein phosphorylation. Am J Physiol Cell Physiol 307:C442-54 (2014). PubMed: 24965592
  • Henriksson S  et al. The scaffold protein WRAP53ß orchestrates the ubiquitin response critical for DNA double-strand break repair. Genes Dev 28:2726-38 (2014). Human . PubMed: 25512560
  • Zhu Y  et al. Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle. Cell Cycle 13:1756-64 (2014). PubMed: 24694730
  • Ciccia A  et al. Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response. Proc Natl Acad Sci U S A 111:18631-6 (2014). PubMed: 25512513
  • Schröder-Heurich B  et al. Protective role of RAD50 on chromatin bridges during abnormal cytokinesis. FASEB J 28:1331-41 (2014). PubMed: 24344331
  • Leung JW  et al. Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling. PLoS Genet 10:e1004178 (2014). Human . PubMed: 24603765
  • Pang B  et al. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin. Nat Commun 4:1908 (2013). ICC/IF ; Human . PubMed: 23715267
  • Renaud E & Rosselli F FANC pathway promotes UV-induced stalled replication forks recovery by acting both upstream and downstream Pol? and Rev1. PLoS One 8:e53693 (2013). WB, ICC/IF ; Human . PubMed: 23365640
  • Izumiya Y  et al. Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation. PLoS Pathog 9:e1003506 (2013). PubMed: 23990779
  • Ismail IH  et al. CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. Nucleic Acids Res 40:5497-510 (2012). ICC/IF ; Human . PubMed: 22402492
  • Sanz-García M  et al. Vaccinia-related Kinase 1 (VRK1) Is an Upstream Nucleosomal Kinase Required for the Assembly of 53BP1 Foci in Response to Ionizing Radiation-induced DNA Damage. J Biol Chem 287:23757-68 (2012). ICC/IF . PubMed: 22621922
  • Andrin C  et al. A requirement for polymerized actin in DNA double-strand break repair. Nucleus 3:384-95 (2012). PubMed: 22688650
  • Solier S & Pommier Y MDC1 cleavage by caspase-3: a novel mechanism for inactivating the DNA damage response during apoptosis. Cancer Res 71:906-13 (2011). PubMed: 21148072
  • Nakamura AJ  et al. The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle 9:389-97 (2010). ICC/IF ; Human . PubMed: 20046100
  • Wu C  et al. CCL22 is involved in the recruitment of CD4+CD25 high T cells into tuberculous pleural effusions. Respirology 15:522-9 (2010). PubMed: 20337996
  • Cook PJ  et al. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 458:591-6 (2009). PubMed: 19234442
  • Cao L  et al. A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency. Mol Cell 35:534-41 (2009). ICC/IF ; Mouse . PubMed: 19716796
  • Bu Y  et al. Sp1-mediated transcriptional regulation of NFBD1/MDC1 plays a critical role in DNA damage response pathway. Genes Cells 13:53-66 (2008). PubMed: 18173747
  • Dimitrova N & de Lange T MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres. Genes Dev 20:3238-43 (2006). PubMed: 17158742
  • Yoo E  et al. 53BP1 is associated with replication protein A and is required for RPA2 hyperphosphorylation following DNA damage. Oncogene 24:5423-30 (2005). PubMed: 15856006

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