Anti-Measles phosphoprotein antibody [9H4] (ab43820)
Key features and details
- Mouse monoclonal [9H4] to Measles phosphoprotein
- Suitable for: ELISA, WB, ICC/IF
- Isotype: IgG1
Overview
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Product name
Anti-Measles phosphoprotein antibody [9H4] -
Description
Mouse monoclonal [9H4] to Measles phosphoprotein -
Host species
Mouse -
Tested applications
Suitable for: ELISA, WB, ICC/IFmore details -
Species reactivity
Reacts with: Measles virus -
Immunogen
Recombinant phosphoprotein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Constituents: 0.75% Glycine, 1.21% Tris, 2% Sucrose -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
9H4 -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab43820 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
1/2000 - 1/10000.
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WB |
1/200 - 1/1000. Predicted molecular weight: 70 kDa.
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ICC/IF |
1/100 - 1/500.
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Notes |
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ELISA
1/2000 - 1/10000. |
WB
1/200 - 1/1000. Predicted molecular weight: 70 kDa. |
ICC/IF
1/100 - 1/500. |
Target
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Relevance
Measles virus belongs to the Paramyxoviridae family within the Mononegavirales order. Measles phosphoprotein is an essential component of the RNA polymerase and the nascent chain assembly complex. The non-segmented, single stranded, negative sense RNA genome of the virus is encapsidated by the nucleoprotein (N) to form a helical nucleocapsid. This ribonucleoproteic complex is the substrate for both transcription and replication. The RNA-dependent RNA polymerase binds to the nucleocapsid template via its co-factor, the phosphoprotein (P). -
Alternative names
- measles virus antibody
- subacute sclerose panencephalitis virus antibody
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab43820 has been referenced in 5 publications.
- Lv Y et al. Synergism of rMV-Hu191 with cisplatin to treat gastric cancer by acid sphingomyelinase-mediated apoptosis requiring integrity of lipid raft microdomains. Gastric Cancer 24:1293-1306 (2021). PubMed: 34251544
- Lv Y et al. A recombinant measles virus vaccine strain rMV-Hu191 has oncolytic effect against human gastric cancer by inducing apoptotic cell death requiring integrity of lipid raft microdomains. Cancer Lett 460:108-118 (2019). PubMed: 31226409
- Cox RM et al. The structurally disordered paramyxovirus nucleocapsid protein tail domain is a regulator of the mRNA transcription gradient. Sci Adv 3:e1602350 (2017). PubMed: 28168220
- Chung HK et al. Tunable and reversible drug control of protein production via a self-excising degron. Nat Chem Biol 11:713-20 (2015). PubMed: 26214256
- Krumm SA et al. The measles virus nucleocapsid protein tail domain is dispensable for viral polymerase recruitment and activity. J Biol Chem 288:29943-53 (2013). WB . PubMed: 24003217