• Product name

    Anti-MED26 antibody [2216C1a]
    See all MED26 primary antibodies
  • Description

    Mouse monoclonal [2216C1a] to MED26
  • Host species

  • Tested applications

    Suitable for: WB, Dot blot, ChIPmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human MED26.

  • Positive control

    • Recombinant MED26 fragment.
  • General notes

     This product was previously labelled as CRSP7




Our Abpromise guarantee covers the use of ab50619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 37 kDa (predicted molecular weight: 65 kDa).
Dot blot Use at an assay dependent concentration.
ChIP Use at an assay dependent concentration. PubMed: 24466310


  • Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
  • Sequence similarities

    Belongs to the Mediator complex subunit 26 family.
    Contains 1 TFIIS N-terminal domain.
  • Cellular localization

  • Information by UniProt
  • Database links

  • Alternative names

    • Activator recruited cofactor 70 kDa component antibody
    • Activator-recruited cofactor 70 kDa component antibody
    • ARC 70 antibody
    • ARC70 antibody
    • Cofactor required for Sp1 transcriptional activation subunit 7 antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa antibody
    • CRSP 7 antibody
    • CRSP complex subunit 7 antibody
    • CRSP70 antibody
    • MED 26 antibody
    • Med26 antibody
    • MED26_HUMAN antibody
    • Mediator complex subunit 26 antibody
    • Mediator of RNA polymerase II transcription subunit 26 antibody
    • Transcriptional coactivator CRSP70 antibody
    see all


  • Anti-MED26 antibody [2216C1a] (ab50619) + immunized recombinant MED26 fragment

    Predicted band size: 65 kDa
    Observed band size: 37 kDa
    why is the actual band size different from the predicted?

    Note: actual size differs from predicted size as this blot was loaded with MED26 fragment.


This product has been referenced in:

  • Sato S  et al. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme. J Biol Chem 291:26886-26898 (2016). Read more (PubMed: 27821593) »
  • Fowler T  et al. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. PLoS One 9:e87003 (2014). ChIP ; Human . Read more (PubMed: 24466310) »
See all 2 Publications for this product

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab50619.
Please use the links above to contact us or submit feedback about this product.

For licensing inquiries, please contact partnerships@abcam.com

Sign up