Anti-MED26 antibody (ab214367)

Submit a review Submit a question

Key features and details

  • Rabbit polyclonal to MED26
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

Overview

  • Product name

    Anti-MED26 antibody
    See all MED26 primary antibodies

  • Description

    Rabbit polyclonal to MED26

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide within Human MED26 aa 30-65 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    AVLEVISSLEKYPITKEALEETRLGKLINDVRKKTK


    Database link: O95402

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human gastric carcinoma tissue.

  • General notes

     This product was previously labelled as CRSP7

     

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

Our Abpromise guarantee covers the use of ab214367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

  • Sequence similarities

    Belongs to the Mediator complex subunit 26 family.
    Contains 1 TFIIS N-terminal domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • Activator recruited cofactor 70 kDa component antibody
    • Activator-recruited cofactor 70 kDa component antibody
    • ARC 70 antibody
    • ARC70 antibody
    • Cofactor required for Sp1 transcriptional activation subunit 7 antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa antibody
    • CRSP 7 antibody
    • CRSP complex subunit 7 antibody
    • CRSP70 antibody
    • MED 26 antibody
    • Med26 antibody
    • MED26_HUMAN antibody
    • Mediator complex subunit 26 antibody
    • Mediator of RNA polymerase II transcription subunit 26 antibody
    • Transcriptional coactivator CRSP70 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MED26 antibody (ab214367)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MED26 antibody (ab214367)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human gastric carcinoma labeling MED26 with ab214367 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References (0)

Publishing research using ab214367? Please let us know so that we can cite the reference in this datasheet.

ab214367 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Show All Reviews Q&A
Submit a review Submit a question

There are currently no Customer reviews or Questions for ab214367.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com