Anti-MED26 antibody (ab214367)

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Overview

  • Product name

    Anti-MED26 antibody
    See all MED26 primary antibodies

  • Description

    Rabbit polyclonal to MED26

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat

  • Immunogen

    Synthetic peptide within Human MED26 aa 30-65 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    AVLEVISSLEKYPITKEALEETRLGKLINDVRKKTK


    Database link: O95402

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • Human gastric carcinoma tissue.

  • General notes

     This product was previously labelled as CRSP7

     

Properties

Applications

Our Abpromise guarantee covers the use of ab214367 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

  • Sequence similarities

    Belongs to the Mediator complex subunit 26 family.
    Contains 1 TFIIS N-terminal domain.

  • Cellular localization

    Nucleus.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • Activator recruited cofactor 70 kDa component antibody
    • Activator-recruited cofactor 70 kDa component antibody
    • ARC 70 antibody
    • ARC70 antibody
    • Cofactor required for Sp1 transcriptional activation subunit 7 antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7 (70kD) antibody
    • Cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa antibody
    • CRSP 7 antibody
    • CRSP complex subunit 7 antibody
    • CRSP70 antibody
    • MED 26 antibody
    • Med26 antibody
    • MED26_HUMAN antibody
    • Mediator complex subunit 26 antibody
    • Mediator of RNA polymerase II transcription subunit 26 antibody
    • Transcriptional coactivator CRSP70 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MED26 antibody (ab214367)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MED26 antibody (ab214367)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human gastric carcinoma labeling MED26 with ab214367 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

References

ab214367 has not yet been referenced specifically in any publications.

Publishing research using ab214367? Please let us know so that we can cite the reference in this datasheet.

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