Overview

  • Product name

  • Description

    Rabbit polyclonal to MED28/EG1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human MED28/EG1 aa 55-100. The exact sequence is proprietary.
    Sequence:

    CFASLV SQDYVNGTDQ EEIRTGVDQC IQKFLDIARQ TECFFLQKRL


    Database link: Q9H204

  • Positive control

    • HEK293T, RAW 264.7 and PC12 whole cell lysates.
  • General notes

     This product was previously labelled as MED28

     

Properties

Applications

Our Abpromise guarantee covers the use of ab200720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 20 kDa.

Target

  • Function

    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.
  • Tissue specificity

    Widely expressed. Highly expressed in vascular tissues such as placenta, testis and liver.
  • Sequence similarities

    Belongs to the Mediator complex subunit 28 family.
  • Cellular localization

    Nucleus. Cytoplasm. Membrane. According to PubMed:15467741, it is cytoplasmic and mainly membrane-associated.
  • Information by UniProt
  • Database links

  • Alternative names

    • EG1 antibody
    • Endothelial-derived protein 1 antibody
    • FKSG20 antibody
    • Magicin antibody
    • med28 antibody
    • MED28_HUMAN antibody
    • Mediator complex subunit 28 antibody
    • Mediator of RNA polymerase II transcription subunit 28 antibody
    • Merlin and Grb2-interacting cytoskeletal protein antibody
    • Tumor angiogenesis marker EG-1 antibody
    see all

Images

  • All lanes : Anti-MED28/EG1 antibody (ab200720)

    Lane 1 : HEK293T whole cell lysate
    Lane 2 : RAW 264.7 whole cell lysate
    Lane 3 : PC12 whole cell lysate

    Predicted band size: 20 kDa

References

ab200720 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab200720.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up