Medroxyprogesterone 17-acetate, Progesterone receptor agonist (ab142633)

Overview

  • Product name

    Medroxyprogesterone 17-acetate, Progesterone receptor agonist
  • Description

    Angiostatic steroid. Potent progesterone receptor agonist
  • Biological description

    Angiostatic steroid. Inhibit vascularization, collagenolysis, tumor growth and plasmin generation. Synthetic variant of progesterone, and a potent progesterone receptor agonist. Active in vitro and in vivo.
  • Purity

    > 98%
  • CAS Number

    71-58-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Africander D  et al. Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 76:636-52 (2011). Read more (PubMed: 21414337) »
  • Lanari C  et al. The MPA mouse breast cancer model: evidence for a role of progesterone receptors in breast cancer. Endocr Relat Cancer 16:333-50 (2009). Read more (PubMed: 19190078) »
  • Madeddu C  et al. Medroxyprogesterone acetate in the management of cancer cachexia. Expert Opin Pharmacother 10:1359-66 (2009). Read more (PubMed: 19445562) »

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