Product nameAnti-MEF2B antibody
See all MEF2B primary antibodies
DescriptionRabbit polyclonal to MEF2B
Tested applicationsSuitable for: WB, EMSA, IPmore details
Species reactivityReacts with: Mouse, Human
Recombinant fragment, corresponding to amino acids 234-365 of Human MEF2B
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Our Abpromise guarantee covers the use of ab33540 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 39 kDa.|
|EMSA||Use at an assay dependent dilution. Use 0.1µl per sample.|
|IP||Use at an assay dependent dilution. Use 4µl for 1ml cell lysate.|
FunctionTranscriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
Tissue specificityExpressed in skeletal and cardiac muscle and brain.
Sequence similaritiesBelongs to the MEF2 family.
Contains 1 MADS-box domain.
Contains 1 Mef2-type DNA-binding domain.
- Information by UniProt
- MADS box transcription enhancer factor 2 antibody
- MDS1 EVI1 antibody
- Mef2b antibody
This product has been referenced in:
- Pon JR et al. MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation. Nat Commun 6:7953 (2015). IP ; Human . Read more (PubMed: 26245647) »
- Ryan RJ et al. Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma. Cancer Discov 5:1058-71 (2015). Read more (PubMed: 26229090) »