Overview

  • Product name

    MeIQ, Mutagenic agent
  • Description

    Mutagenic agent
  • Biological description

    Mutagenic agent. Induces DNA adduct formation. Induces umu operon expression. Shows carcinogenic effects in vivo. Orally active.
  • CAS Number

    77094-11-2
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3,4-Dimethylimidazo[4,5-f]quinolin-2-amine
  • Molecular weight

    212.25
  • Molecular formula

    C12H12N4
  • PubChem identifier

    62274
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC2=C(C=CC=N2)C3=C1N(C(=N3)N)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Chun YJ Expression of recombinant human cytochrome P450 1A2 in Escherichia coli bacterial mutagenicity tester strain. Arch Pharm Res 21:305-9 (1998). Read more (PubMed: 9875448) »
  • Lee H  et al. Structure-related inhibition of human hepatic caffeine N3-demethylation by naturally occurring flavonoids. Biochem Pharmacol 55:1369-75 (1998). Read more (PubMed: 10076527) »
  • Ohgaki H  et al. Carcinogenicities in mice and rats of IQ, MeIQ, and MeIQx. Princess Takamatsu Symp 16:97-105 (1985). Read more (PubMed: 3842704) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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