Overview

  • Product name
    Anti-Melanoma Inhibitory Activity antibody
    See all Melanoma Inhibitory Activity primary antibodies
  • Description
    Goat polyclonal to Melanoma Inhibitory Activity
  • Host species
    Goat
  • Specificity
    The immunizing peptide represents the N terminus of the mature protein. Reported variants represent identical protein: NP_006524.1, NP_001189482.1.
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Rat, Horse, Guinea pig, Cynomolgus monkey, Rhesus monkey, Gorilla
  • Immunogen

    Synthetic peptide, corresponding to internal sequence amino acids 28-40 of Human Melanoma Inhibitory Activity (NP_006524.1).

  • Positive control
    • Human Glioma lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab166932 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 14 kDa.

Target

  • Function
    Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.
  • Tissue specificity
    All malignant melanoma cell lines tested and infrequently in glioma cell lines.
  • Sequence similarities
    Belongs to the MIA/OTOR family.
    Contains 1 SH3 domain.
  • Post-translational
    modifications
    May possess two intramolecular disulfide bonds.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cartilage derived retinoic acid sensitive protein antibody
    • CD RAP antibody
    • CDRAP antibody
    • Melanoma derived growth regulatory protein precursor antibody
    • Melanoma inhibitory activity protein antibody
    • Melanoma-derived growth regulatory protein antibody
    • Mia antibody
    • MIA_HUMAN antibody
    see all

Images

  • Anti-Melanoma Inhibitory Activity antibody (ab166932) at 1 µg + Human Glioma lysates (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 14 kDa



    Primary incubation was 1 hour.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded section) staining Melanoma Inhibitory Activity in Human spleen with ab166932 at 5 µg/ml

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded section) staining Melanoma Inhibitory Activity in Human Skeletal Muscle with ab166932 at 5 µg/ml

References

ab166932 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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