Overview

  • Product name

    Anti-Melatonin Receptor 1B/MTNR1B antibody - Extracellular domain
    See all Melatonin Receptor 1B/MTNR1B primary antibodies
  • Description

    Rabbit polyclonal to Melatonin Receptor 1B/MTNR1B - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Horse, Monkey, Gorilla, Bat, Elephant
  • Immunogen

    Synthetic peptide corresponding to Human Melatonin Receptor 1B/MTNR1B (extracellular). 16 amino acid peptide from 3rd extracellular domain.
    Database link: P49286

  • Positive control

    • Human retina, skin melanoma and brain tissues.
  • General notes

     This product was previously labelled as Melatonin Receptor 1B

     

Properties

Applications

Our Abpromise guarantee covers the use of ab219615 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
  • Tissue specificity

    Expressed in retina and less in brain and hippocampus.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FGQTL2 antibody
    • Mel 1b antibody
    • Mel 1b melatonin receptor antibody
    • Mel 1B R antibody
    • MEL-1B-R antibody
    • Mel1b antibody
    • Mel1b melatonin receptor antibody
    • Mel1b receptor antibody
    • Mel1BR antibody
    • melatonin receptor 1B antibody
    • Melatonin receptor MEL 1B antibody
    • Melatonin receptor MEL1B antibody
    • Melatonin receptor type 1B antibody
    • MT 2 antibody
    • MT 2 melatonin receptor antibody
    • MT2 antibody
    • MT2 melatonin receptor antibody
    • Mtnr 1b antibody
    • Mtnr1b antibody
    • MTR1B_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human retina tissue labeling Melatonin Receptor 1B/MTNR1B with ab219615 at 10 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skin melanoma tissue labeling Melatonin Receptor 1B/MTNR1B with ab219615 at 10 µg/mL.

  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human brain tissue labeling Melatonin Receptor 1B/MTNR1B with ab219615 at 10 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain glioblastoma tissue labeling Melatonin Receptor 1B/MTNR1B with ab219615 at 10 µg/mL.

References

ab219615 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219615.
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