Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal (ab229544)
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Overview
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Product name
Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal
See all Melatonin Receptor 1B/MTNR1B primary antibodies -
Description
Rabbit polyclonal to Melatonin Receptor 1B/MTNR1B - N-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide within Human Melatonin Receptor 1B/MTNR1B (N terminal). The exact sequence is proprietary. Conjugated to a carrier protein.
Database link: P49286 -
Positive control
- WB: K562, THP-1, U-87 MG, SK-N-SH, IMR32 and SK-N-AS whole cell lysates.
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General notes
This product was previously labelled as Melatonin Receptor 1B
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin
Constituents: PBS, 20% Glycerol -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab229544 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
Target
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Function
High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. -
Tissue specificity
Expressed in retina and less in brain and hippocampus. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 4544 Human
- Omim: 600804 Human
- SwissProt: P49286 Human
- Unigene: 569039 Human
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Alternative names
- FGQTL2 antibody
- Mel 1b antibody
- Mel 1b melatonin receptor antibody
see all
Images
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Western blot - Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal (ab229544)All lanes : Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal (ab229544) at 1/1000 dilution
Lane 1 : K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate
Lane 2 : THP-1 (human monocytic leukemia cell line) whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 40 kDa12% SDS-PAGE gel.
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Western blot - Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal (ab229544)All lanes : Anti-Melatonin Receptor 1B/MTNR1B antibody - N-terminal (ab229544) at 1/1000 dilution
Lane 1 : U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate
Lane 2 : SK-N-SH (human neuroblastoma cell line) whole cell lysate
Lane 3 : IMR32 whole cell lysate
Lane 4 : SK-N-AS whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 40 kDa12% SDS-PAGE gel.
References
ab229544 has not yet been referenced specifically in any publications.
