Overview

  • Product name

    Melittin, apoptotic agent
  • Description

    Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent.
  • Biological description

    Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent. Induces surface-tension disruption and cell lysis. Induces ROS-mediated apoptosis. Induces histamine release. Stimulates muscle contractility and shows antifungal effects in vivo.
  • Purity

    > 98%
  • CAS Number

    20449-79-0
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Lee J & Lee DG Melittin triggers apoptosis in Candida albicans through the reactive oxygen species-mediated mitochondria/caspase-dependent pathway. FEMS Microbiol Lett : (2014). Read more (PubMed: 24766524) »
  • Chen CH  et al. Absorption and folding of melittin onto lipid bilayer membranes via unbiased atomic detail microsecond molecular dynamics simulation. Biochim Biophys Acta : (2014). Read more (PubMed: 24769159) »
  • Maher S & McClean S Melittin exhibits necrotic cytotoxicity in gastrointestinal cells which is attenuated by cholesterol. Biochem Pharmacol 75:1104-14 (2008). Read more (PubMed: 18068148) »

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