Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger (ab141322)

Overview

  • Product name

    Mercaptoethylguanidine (MEG) dihydrobromide, iNOS inhibitor; peroxynitrite scavenger
  • Description

    Selective iNOS inhibitor; peroxynitrite scavenger
  • Alternative names

    • MEG
  • Biological description

    Selective iNOS inhibitor. Anti-inflammatory properties including direct inhibition of COX activity and potent scavenging of hydroxyl radicals and peroxynitrite. Active in vivo.
  • CAS Number

    32665-11-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Moochhala SM  et al. Mercaptoethylguanidine inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expressions induced in rats after fluid-percussion brain injury. J Trauma 59:450-7 (2005). Read more (PubMed: 16294091) »
  • Zingarelli B  et al. Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats. J Pharmacol Exp Ther 287:1048-55 (1998). Read more (PubMed: 9864291) »
  • Szabó C  et al. Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage. J Biol Chem 272:9030-6 (1997). Read more (PubMed: 9083027) »
See 1 Publication for this product

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